For success in treatment of amphetamine dependence is very limited. The few studies of the neuropsychological effects of amphetamine abuse report. Treatment of addiction to amphetamines in addictology clinics in Istanbul had proven to be effective. This plant, cultivated in the countries bordering the south of the Red Sea, contains a very addictive natural amphetamine. Amphetamines can be found in nature as the cathinone contained in the leaves of Catha Edulis (The Khat).

Finally, we investigated naltrexone for the treatment of amphetamine dependence in a randomized placebo-controlled trial.Of the amphetamines, methamphetamine likely has the largest potential for abuse. Overall, the results showed that naltrexone was well tolerated with minimal side effects. Chronic amphetamine therapy who had a stable intraoperative course.Twelve weeks of treatment with naltrexone led to a reduction in both frequency and quantity of drug consumption.

Methamphetamine causes increased activity, decreased appetite, and a general sense of well-being. It was developed early in the 20th century from its parent drug, amphetamine, and was used originally in nasal decongestants and bronchial inhalers. The drug is typically made in clandestine laboratories with relatively inexpensive over-the-counter ingredients.1 Department of Psychiatry and Psychology, Baharan Psychiatric Hospital, Zahedan University of Medical Sciences, Zahedan, IR Iran 2 Psychiatrist, Ilam.Methamphetamine is commonly known as 'speed,' 'meth,' or 'chalk.' In its smoked form, it is often referred to as 'ice,' 'crystal,' 'crank,' and 'glass.' It is a white, odorless, bitter-tasting crystalline powder that easily dissolves in water or alcohol.

Because the pleasurable effects disappear even before the drug concentration in the blood falls significantly, users try to maintain the high by bingeing on the drug. This results in methamphetamine being present in the brain longer, which ultimately leads to prolonged stimulant effects.As with similar stimulants, methamphetamine is most often used in a 'binge and crash' pattern. Methamphetamine has a much longer duration of action and a larger percentage of the drug remains unchanged in the body. But methamphetamine, like cocaine, results in an accumulation of the neurotransmitter dopamine, which appears to produce the stimulation and feelings of euphoria experienced by the user. Though its behavioral and physiological effects are similar to those of cocaine, there are some major differences in the basic mechanisms of how these drugs work at the cellular level. After the initial rush, there is typically a state of high agitation that in some individuals may lead to violent behavior.Methamphetamine is structurally similar to the neurotransmitter dopamine.

Changes in brain structure and function, including damage to brain cells containing serotonin Cardiovascular collapse, which may cause death Increased wakefulness, physical activity

According to DSM-5, in order for a diagnosis of Stimulant Use Disorder to be made, an individual must demonstrate a pattern of amphetamine, cocaine, or other stimulant use leading to clinically significant impairment or distress, as manifested by at least two of the following symptoms occurring within a 12-month period: Benzodiazepines, for example, are anti- anxiety agents that may be used to help an individual sleep, but that can also be addictive.Clinical diagnosis for amphetamine use falls under the general category of Stimulant Use Disorder. Amphetamine users may also use other drugs inappropriately to manage the side effects of amphetamines. This may cause collapsed veins, tetanus, abscesses and damage to the heart, lungs, liver, and brain.

Prioritizing stimulant use to such an extent that social, occupational, and recreational activities are either given up on completely or are reduced drastically Continuing to use the stimulant in the face of social/interpersonal problems that result from, or are made worse by, the use of the stimulant Demonstrating the inability, due to stimulant use, to maintain obligations for one's job, school, or home life Experiencing a strong desire or urge to use the stimulant Spending a large amount of time procuring, using, or recovering from the effects of the stimulant Desiring to reduce stimulant use, and/or making failed efforts to do so

Withdrawal, as shown by one of the following: The same dose of the stimulant over the same amount of time results in considerably weaker effects Intoxication requires considerably greater amounts of stimulant use than it did previously Tolerance, as shown by one of the following: Continuing to use the stimulant even when the individual knows that it is causing or exacerbating physical and psychological problems

Contingency management interventions, which provide tangible incentives in exchange for engaging in treatment and maintaining abstinence, have also been shown to be effective.There are no specific medications that counteract the effects of amphetamines or that prolong abstinence from and reduce the abuse of amphetamines. The Matrix Model, for example, is a comprehensive behavioral treatment approach that combines behavioral therapy, family education, individual counseling, 12-step support, drug testing, and encouragement for non-drug-related activities it has been shown to be effective in reducing amphetamine abuse. Adults, according to the DSM-5.The most effective treatments for amphetamine addiction are cognitive behavioral intervention and contingency management models. Symptoms of withdrawal diminish as a result of the use of the stimulant (or similar substances)The tolerance and withdrawal criteria are not considered to be met if the stimulant is used only under appropriate medical supervision.The estimated 12-month prevalence of a stimulant use disorder involving amphetamines is 0.2 percent among U.S.

This medication and others are currently in clinical trials, while new compounds are being developed and studied in preclinical models. Recent findings indicate that bupropion, the anti-depressant marketed as Wellbutrin, may reduce a methamphetamine-induced high as well as drug cravings elicited by drug-related cues.

Treatment For Amphetamine Dependence